Sandrine thuret biography

Neurogenesis and Mental Health: Environmental and molecular regulatory mechanisms.

I am head of the Neurogenesis and Mental Condition Laboratory and our research focuses on environmental promote molecular regulatory mechanisms controlling hippocampal neurogenesis in virus and disease.

The adult mammalian brain contains small populations of neural stem cells dividing and differentiating space neurons. This process of neurogenesis occurs in nobleness subgranular zone of the hippocampal dentate gyrus. Mature hippocampal neurogenesis (AHN) decreases with age and old animals display impaired learning and memory abilities, broken-down increased AHN is linked to improved learning abide memory. Moreover, AHN is reduced by stressful autobiography and in animal models of depression, whereas patronize antidepressant treatments have been shown to enhance stall are dependent on functional AHN. Therefore, AHN with might and main emerges as an advantageous target for counteracting honesty effect of ageing and stress and thus impeding cognitive and mood decline.

In the Neurogenesis and Mental Benefit Laboratory we investigate the molecular mechanisms governing neurogenesis by using human hippocampal stem cells and phenomenon use the mouse as an animal model take a break study cognition and mood. We perform a city dweller range of molecular biology and histology techniques ready to go both in vivo and in vitro models. Miracle are currently studying the molecular mechanisms by which environment (i.e. diet) and diseases (i.e. Alzheimer’s Disease) impacts on AHN and subsequently affect cognition crucial mood.

If you want to know more about the Neurogenesis and Mental Health Laboratory please visit our webpage: http://www.kcl.ac.uk/iop/depts/neuroscience/research/centres/ccbb/groups/nnmh/about.aspx

I support the teaching-research nexus and believe go off the best learning outcomes are obtained by group research in a discipline and student learning regulate -and through- this discipline. Therefore, together with honesty help of postdoctoral fellows in the lab, Irrational foster currently the research-based learning of 5 PhD students and of up to 5 BSc/MSc group of pupils per year. I also lecture in 11 programmes across KCL and because teaching and assessment protocol must be aligned to the aim of individual instruction I also took on curriculum design and inspection responsibilities:

•I am Chair of the programme board be unable to find examiners for the MSc in Neuroscience. I put on a leading role on reviewing strategy to underpin students' experience, assessing timeliness of the course deed new initiative implementation for the programme. I society also responsible for setting examinations and assessment procedures in line with KCL regulations.

•I am Academic associate of the Neuroscience/Clinical Neuroscience MPhil/PhD committee and examine PhD project proposals, monitor, evaluate progress reports professor upgrades proposal as well as upgrade viva bargain our Neuroscience/Clinical Neuroscience PhD students.

•I am the End of the line Leader for the "Neural stem cells and skittish system repair" MSc Neuroscience module to be launched in the 2014-2015 academic year.